BDBM50302107 CHEMBL567893::Grassystatin A
SMILES COC(=O)[C@@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@H](C)NC(=O)[C@@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](OC(=O)[C@@H](OC(=O)[C@H](C(C)C)N(C)C)C(C)C)C(C)C)[C@@H](C)O
InChI Key InChIKey=JZYWSTGTBRHGTL-BIXXXADNSA-N
Data 75 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50302107
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of cathepsin D in human MCF7 cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin D after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of cathepsin D in human MCF7 cells treated for 1 hr measured after washout and trypsin treatment by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of cathepsin D by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of cathepsin D using MCA-KPILFFRLK(Dnp)-D-R-NH2 as substrate incubated for 10 to 15 mins prior to substrate addition measured every 5 min ...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of human liver cathepsin D using Mca-Gly-Lys-Pro-Ile-Leu-PhePhe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate pretreated for 15 mins followed b...More data for this Ligand-Target Pair